Stocks held by ARK Invest’s flagship innovation fund have seen huge losses. Here are the fund’s 10 biggest losers.

• Ark Invest's flagship ETF is sitting on massive losses, with individual holdings down as much as 93%.
• The fund has significantly underperformed the broader stock market, and only one of its top 10 holdings is in the green.
• These are the 10 biggest losing stocks held by the ARK Innovation ETF.

It's been a tough stretch for Cathie Wood and her suite of ARK Invest ETFs.

Ark Invest's flagship innovation ETF, which trades under the ticker symbol "ARKK," has seen massive losses since it peaked in February 2021.

The ARKK ETF is down 72% since its February 19, 2021 peak. Over the same time period, the Nasdaq 100, its primary benchmark, has soared 39% and it sitting at record highs. Year-to-date, the ARKK ETF is down 15% while the Nasdaq 100 is up 12%.

And the losses keep piling up for ARKK, which manages $6.3 billion, down from its peak of about $28 billion in assets under management.

According to data from Cathie's Ark, a website that tracks the daily trades of ARK Invest's ETFs, only one of ARKK's top 10 stock holdings—Tesla—is in the green since it was added to the portfolio. And of the 35 stocks held in the portfolio, only seven stocks are positive. 

Here are the 10 biggest losers held in the ARKK ETF, according to data from Cathie's Ark. 

10. Intellia Therapeutics

ARKK average cost basis: $62.04
Current price: $24.67
% Change: -59.9%

9. UiPath

ARKK average cost basis: $62.44
Current price: $18.98
% Change: -69.5%

8. Roku

ARKK average cost basis: $243.88
Current price: $56.67
% Change: -77.0%

7. Zoom Video

ARKK average cost basis: $278.55
Current price: $63.12
% Change: -77.6%

6. Verve Therapeutics

ARKK average cost basis: $28.17
Current price: $5.25
% Change: -81.0%

5. Unity Technologies

ARKK average cost basis: $104.43
Current price: $19.37
% Change: -81.2%

4. 10x Genomics

ARKK average cost basis: $153.19
Current price: $22.67
% Change: -85.0%

3. Pacific Biosciences

ARKK average cost basis: $19.84
Current price: $1.88
% Change: -90.2%

2. Teladoc Health

ARKK average cost basis: $163.91
Current price: $11.43
% Change: -93.0%

1. Ginkgo Bioworks

ARKK average cost basis: $9.99
Current price: $0.66
% Change: -93.4%