Bradley Cooper and his girlfriend, supermodel Irina Shayk, have split after four years together, which means Cooper and his “A Star Is Born” co-star Lady Gaga are now both single.

Cooper and Gaga play lovers Jackson and Aly in the movie and their on-screen chemistry was palpable for fans. The two artists often spoke about that chemistry during the press tour.

In an interview with Vogue, Gaga said she felt a connection with Cooper from the first moment she met him.

“The second that I saw him, I was like, ‘Have I known you my whole life?'” Gaga said. “It was an instant connection, instant understanding of one another.”

Cooper seconded the connection while describing why he cast her in his directorial debut while at the Venice Film Festival. According to Variety, the 43-year-old actor "fell in love with her face and eyes."

Read more: 14 of the best moments between Bradley Cooper and Lady Gaga on the 'Star Is Born' press tour

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Foto: Bradley Cooper and Lady Gaga in "A Star Is Born."sourceWarner Bros.

They sparked romance speculation in early 2019 as they proved their chemistry during their performance of "Shallow" from "A Star is Born" at the 2019 Oscars.

Following the performance, Gaga told Jimmy Kimmel on "Jimmy Kimmel Live" that the two were just acting.

"Yes, people saw love and guess what? That's what we wanted you to see," she said. "I'm an artist and I guess we did a good job. Fooled ya!"

Read more: Lady Gaga says she and Bradley Cooper wanted people to think they were in love during their Oscars performance

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Foto: Lady Gaga and Bradley Cooper sparked romance speculation with their chemistry onstage.sourceEd Herrera via Getty Images

Fans of the movie are taking the opportunity of the two both being single to create hilarious Twitter memes about the stars finally getting together.

Fans are having fun shipping the couple.

Some people are also poking fun at movie fans who want the couple together.

Read more: Bradley Cooper and Irina Shayk have reportedly split after 4 years together

People Magazine broke the news of Cooper and Shayk's split and sources confirmed the news to US Weekly.

The two began dating in 2015 and have a daughter, Lea De Seine Shayk Cooper, who was born in 2017.

Gaga announced her engagement to Christian Carino in October 2018, but they split before the Oscars in February.